Summary: Between 2015 and 2017, 96 patients had 3 Gold Anchor fiducial markers placed in conjunction with transperineal SpaceOar placement into the prostate at the University of Florida Health Proton Therapy Institute (UFPTI). None of these patients developed sepsis.
The authors write in their discussion “Bacterial UTI following fiducial placement to facilitate treatment planning and delivery for patients undergoing definitive RT for prostate cancer is a potentially life-threatening complication that can often result in sepsis, hospitalization, intensive care unit, and sometimes death. The incidence of this complication is rising, probably due to the widespread use of antibiotics and the consequential development of antibiotic resistant organisms”.